Paddleboats would be hilarious to watch. Sometimes I'm down there and we have to wait for the train bridge, if it's a strong day you have to leave leave both engines in reverse just to hold position between the jetties. I can't imagine a paddleboat in that current. It would be more like a flume ride.
Underneath the parking lot their isn't much of a current. That won't change if it is exposed to air. So, it would be fine for paddleboats. Wouldn't be able to explore as big an area like in Baltimore, but that parking lot area is big enough for a dumb little tourist thing. Obviously, you'd need a rope to keep paddlers away from the channel, which would be like a flume ride (that could be an up-charge). Of course, having a closed-off area shuts it down to regular boat traffic, so I'm not supporting the plan.
The only other thing that might get sticky: there is a concrete slab at the river walk adjacent to the parking garage that was supposed to be a restaraunt-obviously never built. The value of whomever owns that land will certainly plummet. However, I think it's still probably doable.
The slab in front of the Berkman garage? I don't see how this would be a problem for that. They'd still have access to the parking garage, so people could get there. If anything, it would have a better view and more exclusive location. They wouldn't lose foot access, the building just wouldn't be right on the road.