All too many of these multi-level parking structures present a uniform "HEY, here I am, a garage" facade on all sides, with no regard for the ambiance of the area or the general fit.
For a change, I would recommend that the prominent side of a garage be a multi-story multi-use facade of retail with office space above, backed by said garage, with entrances/exits to the rear (or side, but not the front), effectively hiding the fact that this is a potentially ugly but necessary structure. Provision could be made for secure access from the garage to the tenant spaces while the public takes the elevator or stairs to the ground level exiting to the main drag and the amenities of the area. This would also ensure that everybody renting, owning or using the built out spaces would have a front row seat to the good side and not be overlooking the alley or parking lots.